It is an essential prerequisite to recognize pre-analytical factors that can affect the test material before, during, and after sample collection and prior to measurement.

It should also be noted that suppression of the immune response—whether congenital, acquired, or medication-induced—may impair both the humoral immune response (antibody production by B cells) and the cellular immune response (T-cell reactivity).

Our influence on the complex pre-analytical phase is limited to providing you with suitable collection and transport materials, as well as the necessary information.

Proper sample handling during the pre-analytical phase (e.g., blood collection technique, transport) significantly impacts the reliability of laboratory analyses and thus contributes greatly to quality assurance.

Pre-analytical errors are a frequent cause of clinically implausible findings and may lead to misinterpretation and inappropriate treatment.

Most interferences can be avoided through correct sample collection, the appropriate choice of collection containers, and rapid sample transport.

All analyses are performed in accordance with the guidelines of the German Medical Association (RiLiBÄK).

Since most steps in the pre-analytical process lie outside the laboratory’s direct control, the following outlines the most important aspects briefly.

The information provided here aims to minimize pre-analytical errors and thereby create the conditions for reliable test results.

Further information on preanalytics can be found on our website under “Forms and Checklists.” Additional details can be obtained by phone or via our contact form.

Before sample collection, the required collection tubes (check expiry date!) should be prepared and labeled with the necessary information.

To prevent sample mix-ups and ensure correct identification, samples must be clearly and legibly labeled or barcoded directly on the sample containers containing the specimen—not on the protective sleeve or transport bag.

For complete blood count and EliSpot/iSpot tubes, it is crucial to fill them exactly up to the mark, as the reagents contained are prepared for a specific volume ratio.