Tests

Tickplex

The TickPlex assay is conducted based on an ELISA. Compared to other ELISA assays, this test includes a new antigen for Borrelia persisters.

Tickplex3

First immunoassay for persistent forms

The TickPlex is an accredited test and can be used in various stages of disease. The TickPlex Plus allows for simultaneous determination of IgM and IgG antibodies for multiple bacterial and viral pathogens. With its high sensitivity of approximately 95% and specificity of approximately 98%, it outperforms comparable IFT testing methods to date.

Testing with the TickPlex Plus detects antibodies against the pathogens Ehrlichia, Mycoplasma, Bartonella, Rickettsia, Babesia, EBV, Parvovirus, and Coxsackie viruses using the more sensitive and specific ELISA compared to all previously available IFT testing methods. The results of the TickPlex must always be evaluated by the therapist in conjunction with the patient's clinical symptoms and differential diagnoses. The TickPlex can be used in various stages of disease.

Information about the certification of the TickPlex:

Tezted ISO 13485 Certificate

Tickplex Validation Process

EU declaration of conformity for Tickplex Plus

What is tested with the Tickplex Basic IgG/IgM?

Lyme Borreliosis

What is tested with the Tickplex Plus IgG/IgM?

Lyme borreliosis
Ehrlichia & Anaplasma
Bartonella
Babesia
Mycoplasma
Rickettsia
Epstein-Barr-Virus (EBV)
Coxsackievirus
Parvovirus B19

Additional testing recommendations:

Negative results of antibodies by the modern TickPlex assay may not exclude an infection due to potential seronegativity. Therefore, we recommend the following additional test methods for any patient suspected of chronic borreliosis:

Borrelia EliSpot – actual T-cell activity

CD3-/CD57+ cell count – chronic T-cell activity