Afecțiuni
HHV6-Virus
HHV-6 is a commonly occurring virus of the herpesvirus family and typically causes roseola infantum (also known as exanthema subitum) characterized by high fever and a distinctive skin rash. It can also be associated with other conditions such as meningitis, encephalitis, and myocarditis.
General Information, Diseases, and Associations
HHV-6 (Human Herpesvirus 6) is a commonly occurring virus from the herpesvirus family. There are two subtypes of HHV-6, HHV-6A and HHV-6B. HHV-6B is the more common cause of infections in early childhood, while HHV-6A is associated with more severe diseases such as multiple sclerosis, encephalitis, and brain tumors. Transmission primarily occurs through saliva, although vertical (from mother to child) and horizontal (between children) transmission routes are known. HHV-6 remains latent in the body after primary infection and can be reactivated under certain circumstances, such as in immunocompromised individuals.
HHV-6 (Humanes Herpesvirus 6) is associated with various diseases and health conditions, including:
Roseola infantum (Exanthema subitum or Sixth disease): Typically accompanied by high fever and a characteristic skin rash.
Meningitis (inflammation of the membranes surrounding the brain and spinal cord): Characterized by neck stiffness, fever, headache, and sensitivity to light.
Encephalitis (inflammation of the brain): Can lead to headaches, confusion, and neurological symptoms.
Myocarditis (inflammation of the heart muscle): Can lead to arrhythmias and heart failure.
Brain tumors: Associated with brain tumors.
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HHV6-Virus
Humanes Herpes Virus 6 (HHV-6)
Saliva: shedding of viral particles into saliva (prevalance of HHV-6 between 3 and 90% in saliva), latency in salivary glands, haematopoetic (blood-building) system.
Exanthema subitum (Roseola infantum, sixth disease) with high temperature followed by a rash.
Co-factor in Chronic fatique syndrome (CFS), Multiple Sclerosis (neurovirulent), Hashimoto´s thyroiditis, cancer (Kaposi´s sarkoma), temporal lobe epilepsy, optic neuritis, hepatic dysfunction/failure, fibromyalgia, AIDS, cancer temporal lobe epilepsy, reactivation by organ transplantation: encephalitis, pneumonitis, bone marrow suppression.
immune suppression
